Anti-Human/Mouse/Rat HACE1 Polyclonal Antibody

HACE1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1), also known as KIAA1320, is a 909 amino acid protein that localizes to both the cytoplasm and the endoplasmic reticulum and contains one HECT domain and six ANK repeats. Expressed in kidney, heart and brain, HACE1 functions as an E3 ubiquitin-protein ligase that interacts with the proteasome and is thought to play a role in protein degradation. HACE1 is downregulated in Wilms tumor, suggesting a possible role in tumor suppression.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09116
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human HACE1
Specificity Expressed in multiple tissues including heart, brain and kidney.1 Publication
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q8IYU2
Concentration 1.5 mg/mL
Dilution IHC 1:100-1:200
Formulation
Application IHC,ELISA
Other Names E3 ubiquitin-protein ligase HACE1,HACE 1,HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1,KIAA1320
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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