Anti-Human/Mouse/Rat GRK2 Polyclonal Antibody

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11170
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human ADRBK1
Specificity Expressed in peripheral blood leukocytes.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P25098
Concentration 0.5 mg/mL
Dilution IHC 1:100-1:300
Formulation
Application IHC,ELISA
Other Names ADRBK1,Adrenergic beta receptor kinase 1,ARBK1,BARK,BARK1,Beta adrenergic receptor kinase 1,Beta ARK 1,Beta ARK1,Beta-adrenergic receptor kinase 1,Beta-ARK-1,FLJ16718,G protein coupled receptor kinase 2,G-protein coupled receptor kinase 2,GRK2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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