Data Sheet | Click for Datasheet |
---|---|
Catalog Number | PA12257 |
Size | 100μl |
Host Type | Rabbit |
Immunogen | Recombinant protein of human GREM1 |
Specificity | Highly expressed in small intestine, fetal brain and colon. Expression is restricted to intestinal subepithelial myofibroblasts (ISEMFs) at the crypt base. In subjects with HMPS1, by contrast, GREM1 is expressed, not only in basal ISEMFs, but also at very high levels in epithelial cells (predominantly colonocytes), with expression extending most of the way up the sides of the crypt. Weakly expressed in brain, ovary, prostate, pancreas and skeletal muscle. In brain found in the region localized around the internal capsule in the large subcortical nuclei, including caudate, putamen, substantia nigra, thalamus and subthalamus. Predominantly expressed in normal cells including neurons, astrocytes and fibroblasts. |
Isotype | IgG |
Reacitivity | Human,Mouse,Rat |
Clone | |
Uniprot | O60565 |
Concentration | 0.3 mg/mL |
Dilution | WB 1:500-1:2000 |
Formulation | Application | WB,ELISA |
Other Names | BMP antagonist 1,Cell proliferation inducing gene 2 protein,Cell proliferation-inducing gene 2 protein,CKTSF1B1,colorectal adenoma and carcinoma 1,Cysteine knot superfamily 1,Cysteine knot superfamily 1,BMP antagonist 1,Cysteine knot superfamily BMP antagonist 1,DAN domain family member 2,DAND2,Down regulated in Mos-transformed cells protein,Down-regulated in Mos-transformed cells protein,DRM,grem1,GREM1,Gremlin 1 homolog,cysteine knot superfamily,Gremlin 1 like protein,Gremlin 1,cysteine knot superfamily,homolog,GREMLIN,Gremlin-1,Gremlin1,IHG-2,IHG2,Increased in high glucose 2,Increased in high glucose protein 2,PIG2,Proliferation inducing gene 2,proliferation inducing gene 2 protein |
Storage | Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C. |
Postscript | For research use only, not for use in diagnostic procedures. |
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