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Anti-Human/Mouse/Rat GPR120 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Receptor for medium and long-chain free fatty acid (FAA). Signals via a G(q)/G(11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti-inflammatory effects particulary in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1 dependent effect but independent of G(q)/G(11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage-induced tissue inflammation. May mediates the taste of fatty acids.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04260
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human GPR120
Specificity Abundant expression in the intestinal tract.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q5NUL3
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:5000
Formulation
Application WB,IF,ELISA
Other Names BMIQ10,FFAR4,Free fatty acid receptor 4,G protein coupled receptor 120,G protein coupled receptor 129,G protein coupled receptor GT01,G protein coupled receptor PGR 4,G protein coupled receptor PGR4,G-protein coupled receptor 120,G-protein coupled receptor 129,G-protein coupled receptor GT01,G-protein coupled receptor PGR4,GPR 120,GPR 129,GPR120,GPR129,GT01,HGNC:19345,MGC119984,O3FA1,O3FAR1,Omega-3 fatty acid receptor 1,PGR 4,PGR4
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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