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Anti-Human/Mouse/Rat GEMIN2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes one of the proteins found in the SMN complex, which consists of several gemin proteins and the protein known as the survival of motor neuron protein. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10779
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human GEMIN2
Specificity
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O14893
Concentration 0.3 mg/mL
Dilution WB 1:200-1:1000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names Component of gems 2,Gem (nuclear organelle) associated protein 2,Gem associated protein 2,GEMI2,Gemin-2,gemin2,SIP 1,SIP-1,SIP1,SIP1 delta,SIP1-delta,SMN interacting protein 1,SMN interacting protein 1 delta,SMN-interacting protein 1,Survival interacting protein 1,Survival of motor neuron protein interacting protein 1,Survival of motor neuron protein-interacting protein 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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