Anti-Human/Mouse/Rat FTO Polyclonal Antibody

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06204
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human FTO.
Specificity Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9C0B1
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names AlkB homolog 9,ALKBH9,Alpha-ketoglutarate-dependent dioxygenase FTO,AW743446,Fat mass and obesity-associated protein,FATSO,MOUSE,HOMOLOG OF,Fto,FTO,GDFD,KIAA1752,mKIAA1752,Protein fatso
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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