Anti-Human/Mouse/Rat FHL1 Polyclonal Antibody

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12092
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human FHL1
Specificity Isoform 1 is highly expressed in skeletal muscle and to a lesser extent in heart, placenta, ovary, prostate, testis, small intestine, colon and spleen. Expression is barely detectable in brain, lung, liver, kidney, pancreas, thymus and peripheral blood leukocytes. Isoform 2 is expressed in brain, skeletal muscle and to a lesser extent in heart, colon, prostate and small intestine. Isoform 3 is expressed in testis, heart and skeletal muscle.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q13642
Concentration 0.6 mg/mL
Dilution WB 1:500-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names bA535K18.1,FHL 1,FHL 1B,FHL-1,FHL1,FHL1 protein,FHL1,FHL1A,FHL1B,FLH1A,Four and a half LIM domains 1,Four and a half LIM domains protein 1,Four and a half Lin11 Isl 1 and Mec 3 domains 1,four-and-a-half Lin11,Isl-1 and Mec-3,KYO T,KYOT,mouse,homolog of,LIM protein SLIMMER,MGC111107,RAM14-1,RBMX1A,RBMX1B,RBP associated molecule 14-1,RP11-535K18.1,Skeletal muscle LIM protein 1,Skeletal muscle LIM-protein 1,SLIM 1,SLIM,SLIM-1,SLIM1,SLIMMER,XMPMA
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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