Anti-Human/Mouse/Rat FAT3 Polyclonal Antibody

FAT1, FAT2, FAT3 and FAT4 are human homologs of Drosophila Fat, which is involved in tumor suppression and planar cell polarity (PCP). The atypical cadherin Fat3 ensures that retinal amacrine cells (ACs) develop this unipolar morphology. Fat3 expression was restricted to the nervous system, for example in the brain, it is expressed in a variety of regions and axon fascicles. However, its strongest expression was observed in the olfactory bulb and retina.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10068
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human FAT3
Specificity Expressed in ES cells, primitive neuroectoderm, fetal brain, infant brain, adult neural tissues and prostate.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q8TDW7
Concentration 0.2 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names Cadherin family member 15,CDHF15,CDHR10,FAT tumor suppressor homolog 3,Fat3,FAT3,hFat3,KIAA1989,Protocadherin Fat 3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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