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Anti-Human/Mouse/Rat ERBB4 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11731
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human ERBB4
Specificity Expressed at highest levels in brain, heart, kidney, in addition to skeletal muscle, parathyroid, cerebellum, pituitary, spleen, testis and breast. Lower levels in thymus, lung, salivary gland, and pancreas. Isoform JM-A CYT-1 and isoform JM-B CYT-1 are expressed in cerebellum, but only the isoform JM-B is expressed in the heart.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q15303
Concentration 0.3 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names 4ICD,ALS19,Avian erythroblastic leukemia viral oncogene homolog 4,Avian erythroblastic leukemia viral v erb b2 oncogene homolog 4,E4ICD,EC 2.7.10.1,Erbb4,ERBB4 intracellular domain,ERBB4,HER 4,HER4,human epidermal growth factor receptor 4,Mer4,MGC138404,Oncogene ERBB4,p180erbB4,Proto-oncogene-like protein c-ErbB-4,Receptor protein tyrosine kinase erbB 4 precursor,Receptor tyrosine protein kinase erbB 4,s80HER4,Tyrosine kinase type cell surface receptor HER4,Tyrosine kinase-type cell surface receptor HER4,v erb a avian erythroblastic leukemia viral oncogene homolog like 4,v erb a erythroblastic leukemia viral oncogene homolog 4,v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian),V-ERB-B2 avian erythroblastic leukemia viral oncogene homolog 4,Verba avian erythroblastic leukemia viral oncogene homolog like 4,Verba erythroblastic leukemia viral oncogene homolog 4,VERBB2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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