Anti-Human/Mouse/Rat EPHB1/2 Polyclonal Antibody

Ephrin receptors bind members of the ephrin ligand family. They are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. They make up the largest subgroup of the receptor tyrosine kinase (RTK) family. Eph receptor B1 (EphB1) and Eph receptor B2 (EphB2) are receptors for ephrin-B family members. Developing and adult neural tissue express nearly all of the Ephrin receptors and ephrin ligands. Ephrins and ephrin receptors also play a significant role in angiogenesis. EphB2 acts as a tumor suppressor.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03773
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human EphB1/2 around the non-phosphorylation site of Y594/604.
Specificity EPHB1 is Preferentially expressed in brain.EPHB2 isBrain, heart, lung, kidney, placenta, pancreas, liver and skeletal muscle. Preferentially expressed in fetal brain.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names EPHB1,ELK,EPHT2,HEK6,NET,Ephrin type-B receptor 1,ELK,EPH tyrosine kinase 2,EPH-like kinase 6,EK6,hEK6,Neuronally-expressed EPH-related tyrosine kinase,NET,Tyrosine-protein kinase receptor EPH-2,EPHB2,DRT,EPHT3,EPTH3,ERK,
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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