Anti-Human/Mouse/Rat EPAS1 Polyclonal Antibody

This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06460
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human EPAS-1 around the non-acetylation site of K385.
Specificity Expressed in most tissues, with highest levels in placenta, lung and heart. Selectively expressed in endothelial cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q99814
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names Basic helix loop helix PAS protein MOP2,Basic-helix-loop-helix-PAS protein MOP2,bHLHe73,Class E basic helix-loop-helix protein 73,ECYT4,Endothelial PAS domain containing protein 1,Endothelial pas domain protein 1,Endothelial PAS domain-containing protein 1,EPAS 1,EPAS-1,EPAS1,EPAS1,HIF 1 alpha like factor,HIF 2 alpha,HIF-1-alpha-like factor,HIF-2-alpha,HIF2-alpha,HIF2A,HLF,Hypoxia inducible factor 2 alpha,Hypoxia inducible factor 2 alpha subunit,Hypoxia-inducible factor 2-alpha,Member of PAS protein 2,Member of pas superfamily 2,MOP 2,MOP2,PAS domain-containing protein 2,PASD2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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