Anti-Human /Mouse /Rat EIF4E Polyclonal Antibody

Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03360
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human EIF4E (Ab-209)
Specificity
Isotype IgG
Reacitivity Human ,Mouse ,Rat
Clone
Uniprot P06730
Concentration 1 mg/mL
Dilution WB 1:500-1:1000, IHC 1:50-100, IF/ICC 1:100-1:200
Formulation
Application WB,IHC,IF
Other Names AUTS19,CBP,eIF 4E,eIF 4F 25 kDa subunit,EIF 4F,eIF-4E,eIF-4F 25 kDa subunit,eIF4E,EIF4E1,EIF4EL1,EIF4F,Eukaryotic translation initiation factor 4 E,Eukaryotic translation initiation factor 4E,Eukaryotic translation initiation factor 4E like 1,IF4E,Messanger RNA Cap Binding Protein eIF 4E,MGC111573,mRNA cap binding protein,mRNA cap-binding protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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