Anti-Human/Mouse/Rat E2F6 Polyclonal Antibody

This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03630
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human E2F-6
Specificity Expressed in all tissues examined. Highest levels in placenta, skeletal muscle, heart, ovary, kidney, small intestine and spleen.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O75461
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names E2F 6,E2F binding site modulating activity protein,E2F transcription factor 6,E2F transcription factor 6 isoform 1,E2F-6,E2F6,E2F6,EMA,MGC111545,Transcription factor E2F6
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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