Anti-Human/Mouse/Rat E2F4 Polyclonal Antibody

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-4 binds with high affinity to RBL1 and RBL2. In some instances, can also bind RB protein.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06459
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human E2F-4 around the non-acetylation site of K96.
Specificity Found in all tissue examined including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q16254
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000-1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names E2F 4,E2F transcription factor 4,E2F transcription factor 4 p107/p130 binding,E2F-4,E2F4,E2F4,p107/p130 binding protein,Transcription factor E2F 4,Transcription factor E2F4
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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