Anti-Human/Mouse/Rat DPYD Polyclonal Antibody

The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06374
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human DPYD.
Specificity Found in most tissues with greatest activity found in liver and peripheral blood mononuclear cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q12882
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names DHP,DHPDHase,Dihydropyrimidine dehydrogenase [NADP(+)],Dihydropyrimidine dehydrogenase [NADP+],Dihydropyrimidine dehydrogenase,Dihydrothymine dehydrogenase,Dihydrouracil dehydrogenase,DPD,DPYD,DPYD,MGC132008,MGC70799,OTTHUMP00000058954
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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