Anti-Human/Mouse/Rat DNA Ligase1 Polyclonal Antibody

This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12205
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human LIG1
Specificity
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P18858
Concentration 1 mg/mL
Dilution IHC 1:100-1:300
Formulation
Application IHC,ELISA
Other Names DNA ligase 1,DNA ligase I,DNLI1,LIG 1,lig1,Ligase I DNA ATP dependent,MGC117397,MGC130025,Polydeoxyribonucleotide synthase [ATP] 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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