Anti-Human/Mouse/Rat DKC1 Polyclonal Antibody

This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03624
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Dyskerin
Specificity Ubiquitously expressed.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O60832
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Formulation
Application WB,IHC-p,IF,ELISA
Other Names CBF5,CBF5 homolog,Cbf5p homolog,DKC 1,DKC,Dkc1,DKC1,DKCX,Dyskeratosis congenita 1,Dyskeratosis congenita 1 dyskerin,Dyskerin,H/ACA ribonucleoprotein complex subunit 4,NAP 57,NAP57,NOLA 4,NOLA4,Nopp140 associated protein of 57 kDa,Nopp140-associated protein of 57 kDa,Nucleolar protein family A member 4,Nucleolar protein NAP57,snoRNP protein DKC1,XAP 101,XAP101
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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