Anti-Human/Mouse/Rat DDAH1 Polyclonal Antibody

This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid (atRA). DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09871
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human DDAH1
Specificity Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O94760
Concentration 0.2 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names DDAH,DDAH I,DDAH-1,DDAH1,DDAH1,DDAHI,Dimethylargininase 1,Dimethylargininase-1,Dimethylarginine dimethylaminohydrolase 1,N(G),N(G)-dimethylarginine dimethylaminohydrolase 1,NG NG dimethylarginine dimethylaminohydrolase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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