Anti-Human/Mouse/Rat CYLD Polyclonal Antibody

This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09421
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human CYLD
Specificity Detected in fetal brain, testis, and skeletal muscle, and at a lower level in adult brain, leukocytes, liver, heart, kidney, spleen, ovary and lung. Isoform 2 is found in all tissues except kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9NQC7
Concentration 0.7 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names BRSS,CDMT,Cyld,CYLD gene,CYLD,CYLD1,CYLDI,cylindromatosis (turban tumor syndrome),cylindromatosis 1,Deubiquitinating enzyme CYLD,EAC,HSPC057,KIAA0849,MFT,MFT1,Probable ubiquitin carboxyl terminal hydrolase CYLD,SBS,TEM,turban tumor syndrome,Ubiquitin carboxyl-terminal hydrolase CYLD,ubiquitin specific peptidase like 2,ubiquitin thioesterase CYLD,Ubiquitin thiolesterase CYLD,Ubiquitin-specific processing protease CYLD,Ubiquitin-specific-processing protease CYLD,USPL2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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