Anti-Human/Mouse/Rat Cyclin L1 Polyclonal Antibody

Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03344
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human Cyclin L1
Specificity Ubiquitous with higher level in thymus. Overexpression in primary tumors of head and neck squamous cell carcinomas (HNSCC).
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9UK58
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names Ania 6a,CCNL1,CCNL1,Cyclin L,Cyclin L gamma,Cyclin L1 ,Cyclin-L,Cyclin-L1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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