Anti-Human/Mouse/Rat CTDSP1 Polyclonal Antibody

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03180
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human CTDSP1.
Specificity Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9GZU7
Concentration 1 mg/mL
Dilution WB 1:500-1:2000, IHC 1:50-1:200, ELISA 1:5000-1:20000
Formulation
Application WB,IHC,ELISA
Other Names Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1,Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1,CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1,CTD small phosphatase 1,CTDS1,CTDSP1,NIF3,NLI IF,NLI interacting factor 3,NLI-IF,NLI-interacting factor 3,NLIIF,Nuclear LIM interactor interacting factor 3,Nuclear LIM interactor-interacting factor 3,SCP1,Small C-terminal domain phosphatase 1,Small CTD phosphatase 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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