Anti-Human/Mouse/Rat CREB3L2 Polyclonal Antibody

Transcriptional activator which is processed and activated during endoplasmic reticulum stress late phase. Binds to the cAMP response element (CRE) and activates transcription through CRE. Regulates the transcription of unfolded protein response target genes, preventing accumulation of unfolded proteins in damaged neurons. Also regulates the expression of SEC23A, accelerating protein trafficking from the ER to the Golgi thereby playing a key role in chondrocyte differentiation and formation of epiphyseal cartilage.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03109
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human CREB3L2
Specificity Widely expressed with highest levels in placenta, lung, spleen and intestine, and lowest levels in heart, brain, skeletal muscle, thymus, colon and leukocytes. In fetal tissues, the weakest expression is detected in brain and heart.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q70SY1
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names B ZIB transcription factor,Basic transcription factor 2,BBF2 human homolog on chromosome 7,BBF2H7,BZIB transcription factor,cAMP responsive element binding protein 3 like 2,cAMP-responsive element-binding protein 3-like protein 2,CR3L2,Creb3l2,Cyclic AMP-responsive element-binding protein 3-like protein 2,FUS/BBF2H7 protein,MGC131709,MGC71006,Processed cyclic AMP-responsive element-binding protein 3-like protein 2,TCAG_1951439
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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