Anti-Human/Mouse/Rat Cleaved-PLG (V98) Polyclonal Antibody

The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02193
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human Plasminogen HC A short form
Specificity Present in plasma and many other extracellular fluids. It is synthesized in the liver.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P00747
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names Angiostatin,DKFZp779M0222,Plasmin,Plasmin heavy chain A,Plasmin light chain B,Plasminogen,PLG,PLMN
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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