Anti-Human/Mouse/Rat CK-4 Polyclonal Antibody

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04693
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide from human protein
Specificity Detected in the suprabasal layer of the stratified epithelium of the esophagus, exocervix, vagina, mouth and lingual mucosa, and in cells and cell clusters in the mucosa and serous gland ducts of the esophageal submucosa (at protein level). Expressed widely in the exocervix and esophageal epithelium, with lowest levels detected in the basal cell layer.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P19013
Concentration 1mg/mL
Dilution WB 1:500-2000, ELISA 1:10000-20000
Formulation
Application WB,ELISA
Other Names CK 4,CK-4,CK4,CYK4,Cytokeratin 4,Cytokeratin-4,Cytokeratin4,FLJ31692,K2C4,K4,Keratin 4,Keratin,Keratin type II cytoskeletal 4,Keratin-4,Keratin4,KRT 4,Krt4,type II cytoskeletal 4,Type-II keratin Kb4
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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