Anti-Human/Mouse/Rat CK-20 Polyclonal Antibody

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02420
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human KRT20
Specificity Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P35900
Concentration 1 mg/mL
Dilution IHC 1:25-100, ELISA 1:2000-5000
Formulation
Application IHC,ELISA
Other Names K20,CD20,CK20,CK-20,KRT21
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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