Anti-Human/Mouse/Rat CHAC1 Polyclonal Antibody

CHAC1 (ChaC, cation transport regulator homolog 1 (E. coli)) is a 264 amino acid cytoplasmic protein that belongs to the ChaC family. Induced by chemical activators of the unfolded protein response (UPR) pathway, including DTT, tunicamycin and thapsigargin, CHAC1 is a pro-apoptotic member of this pathway and may mediate the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade. Overexpression of CHAC1 may lead to an increase in apoptosis, while suppression of CHAC1 results in subdued apoptosis. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA09068
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human CHAC1
Specificity
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9BUX1
Concentration 0.7 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names Blocks Notch protein,Botch,Cation transport regulator like protein 1,Cation transport regulator-like protein 1,ChaC,ChaC cation transport regulator homolog 1,ChaC cation transport regulator like 1,chac1,CHAC1,Gamma GCT acting on glutathione homolog 1,Gamma-GCG 1,Glutathione-specific gamma-glutamylcyclotransferase 1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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