Anti-Human/Mouse/Rat CFL1 Polyclonal Antibody

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12339
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human CFL1
Specificity Widely distributed in various tissues.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P23528
Concentration 0.1 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names 18 kDa phosphoprotein,CFL 1,CFL,CFL1,COF1,Cofilin 1,Cofilin 1 non muscle,Cofilin,Cofilin non muscle isoform,Cofilin-1,epididymis secretory protein Li 15,HEL-S-15,non-muscle isoform,p18
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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