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Anti-Human/Mouse/Rat CDK5 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Cyclin-dependent kinases (CDKs) are serine/threonine kinases that are activated by cyclins and govern eukaryotic cell cycle progression. While CDK5 shares high sequence homology with its family members, it is thought mainly to function in postmitotic neurons to regulate the cytoarchitecture of these cells. Analogous to cyclins, the regulatory subunits p35 and p39 associate with and activate CDK5 despite the lack of sequence homology.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06770
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human CDK5
Specificity Isoform 1 is ubiquitously expressed. Accumulates in cortical neurons (at protein level). Isoform 2 has only been detected in testis, skeletal muscle, colon, bone marrow and ovary.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q00535
Concentration 0.3 mg/mL
Dilution WB 1:500-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names Cdk 5,Cdk5,CDK5,Cell division protein kinase 5,Crk6,Cyclin dependent kinase 5,Cyclin-dependent kinase 5,Protein kinase CDK5 splicing,PSSALRE,Serine threonine protein kinase PSSALRE,Serine/threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subunit,TPKII catalytic subunit
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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