Anti-Human/Mouse/Rat CD98 Polyclonal Antibody

This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06523
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human CD98.
Specificity Expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. During gestation, expression in the placenta was significantly stronger at full-term than at the mid-trimester stage. Expressed in HUVECS and at low levels in resting peripheral blood T-lymphocytes and quiescent fibroblasts. Also expressed in fetal liver and in the astrocytic process of primary astrocytic gliomas. Expressed in retinal endothelial cells and in the intestinal epithelial cell line C2BBe1.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P08195
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:10000
Formulation
Application WB,ELISA
Other Names 4F2,4F2 cell surface antigen heavy chain,4F2 cell-surface antigen heavy chain,4F2 heavy chain,4F2 heavy chain antigen,4F2,4F2hc,4T2HC,Antigen defined by monoclonal 4F2 heavy chain,Antigen identified by monoclonal antibodies 4F2 TRA1.10 TROP4 and T43,CD 98,CD98,CD98 antigen,CD98 heavy chain,CD98HC,Heavy chain,Lymphocyte activation antigen 4F2 large subunit,MDU 1,MDU1,Monoclonal 44D7,NACAE,Slc3a2,Solute carrier family 3 (activators of dibasic and neutral amino acid transport) member 2,Solute carrier family 3 member 2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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