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Anti-Human/Mouse/Rat CCR4 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA06430
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human CKR-4.
Specificity Predominantly expressed in the thymus, in peripheral blood leukocytes, including T-cells, mostly CD4+ cells, and basophils, and in platelets; at lower levels, in the spleen and in monocytes. Detected also in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expressing the cutaneous lymphocyte antigen (CLA). Expressed in brain microvascular and coronary artery endothelial cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P51679
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names C C chemokine receptor type 4,C C CKR 4,C-C chemokine receptor type 4,C-C CKR-4,CC CKR 4,CC-CKR-4,CCR 4,CCR-4,CCR4,CCR4,CD194,Chemokine (CC motif) receptor 4,chemokine C C motif receptor 4,ChemR13,CKR4,CMKBR 4,CMKBR4,HGCN 14099,K5 5,K5-5,MGC88293
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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