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Anti-Human/Mouse/Rat CBS Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12750
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human CBS
Specificity In the adult strongly expressed in liver and pancreas, some expression in heart and brain, weak expression in lung and kidney. In the fetus, expressed in brain, liver and kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P35520
Concentration 0.2 mg/mL
Dilution WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names AI047524,AI303044,Beta thionase,Beta-thionase,Cbs,Cbs cystathionine beta-synthase,CBS,Cystathionine beta synthase,Cystathionine beta-synthase,EC 4.2.1.22,HIP 4,HIP4,Methylcysteine synthase,MGC18856,MGC18895,MGC37300,OTTHUMP00000109416,OTTHUMP00000109418,Serine sulfhydrase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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