Anti-Human/Mouse/Rat CACNA2D4 Polyclonal Antibody

This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA02385
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human Cacna2d4
Specificity Predominantly expressed in certain types of endocrine cells. Present in the Paneth cells of the small intestine. Also present in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophils of the pituitary. Present at low level in some brain regions such as the cerebellum (at protein level).
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q7Z3S7
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names Calcium channel,voltage dependent,alpha 2/delta subunit 4,RCD4,Voltage dependent calcium channel subunit alpha 2/delta 4,Voltage gated calcium channel alpha(2)delta 4 subunit,Voltage gated calcium channel subunit alpha 2/delta 4,Voltage-dependent calcium channel subunit alpha-2-4,Voltage-dependent calcium channel subunit delta-4
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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