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Anti-Human/Mouse/Rat BACE1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05141
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human BACE Polyclonal
Specificity Expressed at high levels in the brain and pancreas. In the brain, expression is highest in the substantia nigra, locus coruleus and medulla oblongata.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P56817
Concentration 1mg/mL
Dilution WB 1:500-2000, ELISA 1:10000-20000
Formulation
Application WB,ELISA
Other Names APP beta secretase,Asp 2,ASP2,Aspartyl protease 2,BACE 1,BACE,BACE1,BACE1,Beta secretase 1,Beta secretase,Beta site amyloid beta A4 precursor protein cleaving enzyme,Beta site amyloid precursor protein cleaving enzyme 1,Beta site amyloid precursor protein cleaving enzyme,Beta site APP cleaving enzyme 1,Beta site APP cleaving enzyme,Beta-secretase 1,Beta-site amyloid precursor protein cleaving enzyme 1,Beta-site APP cleaving enzyme 1,FLJ90568,HSPC104,Memapsin 2,Memapsin-2,Memapsin2,Membrane associated aspartic protease 2,Membrane-associated aspartic protease 2,Transmembrane aspartic proteinase Asp2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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