Anti-Human/Mouse/Rat B4GALNT1 Polyclonal Antibody

GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.B4GALNT1 (Beta-1,4-N-Acetyl-Galactosaminyltransferase 1) is a Protein Coding gene. Diseases associated with B4GALNT1 include Spastic Paraplegia 26, Autosomal Recessive and Spastic Paraplegia 26. Among its related pathways are Glycosphingolipid biosynthesis - ganglio series and Metabolism. GO annotations related to this gene include transferase activity and acetylgalactosaminyltransferase activity. An important paralog of this gene is B4GALNT2.