Anti-Human/Mouse/Rat ATIC Polyclonal Antibody

This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07481
Size 100μl
Host Type Rabbit
Immunogen Fusion protein of human ATIC
Specificity
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P31939
Concentration 0.2 mg/mL
Dilution WB 1:500-2000, ELISA 1:2000-5000
Formulation
Application WB,ELISA
Other Names AICAR formyltransferase/IMP cyclohydrolase,5 aminoimidazole 4 carboxamide 1 beta D ribonucleotide transformylase/inosinicase,5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase,5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase,5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase,AICAR,AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme,AICAR transformylase,AICARFT,AICARFT/IMPCHASE,ATIC,Bifunctional purine biosynthesis protein PURH,epididymis secretory sperm binding protein Li 70p,FLJ93545,HEL-S-70p,IMP cyclohydrolase,IMP synthase,IMP synthetase,IMPCHASE,Inosinicase,OK/SW-cl.86,Phosphoribosylaminoimidazolecarboxamide formyltransferase,Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase,PUR9,PURH
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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