Anti-Human/Mouse/Rat ATG5 Monoclonal Antibody

Autophagy protein 5 is a protein that in humans is encoded by the ATG5 gene. It is an E3 ubiquitin ligase which is necessary for autophagy due to its role in autophagosome elongation. It is activated by ATG7 and forms a complex with ATG12 and ATG16L1. This complex is necessary for LC3-1 conjugation to PE to form LC3-II.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02743
Size 100μl
Host Type Mouse
Immunogen Recombinant Protein of ATG5
Specificity Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone 8B4
Uniprot Q9H1Y0
Concentration 1mg/mL
Dilution IHC 1:50-300
Formulation
Application IHC-p
Other Names APG 5,APG 5L,APG5,APG5 autophagy 5 like,APG5 like,APG5-like,APG5L,Apoptosis specific protein,Apoptosis-specific protein,ASP,ATG 5,Atg5,ATG5 autophagy related 5 homolog,ATG5,Autophagy protein 5,Autophagy related 5,hAPG5,Homolog of S Cerevisiae autophagy 5,OTTHUMP00000040507
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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