Anti-Human/Mouse/Rat ARHGEF12 Polyclonal Antibody

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA04726
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the Internal region of human LARG
Specificity Ubiquitously expressed. Isoform 2 is found in jejunum and testis.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9NZN5
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names ARHGC,ARHGEF12,KIAA0382,leukemia-associated rho guanine nucleotide exchange factor,Leukemia-associated RhoGEF,PRO2792,Rho guanine exchange factor (GEF) 12,Rho guanine nucleotide exchange factor (GEF) 12,Rho guanine nucleotide exchange factor 12,Similar to Mouse Lsc oncogene
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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