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Anti-Human/Mouse/Rat ANXA1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Annexin I belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. Annexin I protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Since phospholipase A2 is required for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, annexin I may have potential anti-inflammatory activity.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11556
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human ANXA1
Specificity Detected in resting neutrophils (PubMed:10772777). Detected in peripheral blood T-cells (PubMed:17008549). Detected in extracellular vesicles in blood serum from patients with inflammatory bowel disease, but not in serum from healthy donors (PubMed:25664854). Detected in placenta (at protein level) (PubMed:2532504). Detected in liver.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P04083
Concentration 0.3 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB,ELISA
Other Names Annexin 1,Annexin A1,Annexin I (lipocortin I),Annexin I,Annexin-1,AnnexinA1,AnnexinI,ANX 1,ANX A1,ANX1,ANXA 1,ANXA1,ANXA1 protein,ANXA1,Calpactin 2,Calpactin II,Calpactin-2,CalpactinII,Chromobindin 9,Chromobindin-9,Chromobindin9,HGNC:533,Lipocortin 1,Lipocortin I,Lipocortin1,LipocortinI,LPC 1,LPC1,p35,Phospholipase A2 inhibitory protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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