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Anti-Human /Mouse /Rat AKR7A2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA03142
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human AKR7A2
Specificity Detected in brain, liver, small intestine and testis, and at lower levels in heart, prostate, skeletal muscle and spleen. Detected in kidney proximal and distal tubules, endothelial cells lining the Bowman's capsules and some cysts. Detected at low levels in lung and pancreas (at protein level). Widely expressed.
Isotype IgG
Reacitivity Human ,Mouse ,Rat
Clone
Uniprot O43488
Concentration 1.35 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB
Other Names AFAR,AFAR1,AFB1 aldehyde reductase 1,AFB1 AR1,AFB1-AR 1,AFB1AR1,Aflatoxin aldehyde reductase,Aflatoxin B1 aldehyde reductase member 2,Aflatoxin beta1 aldehyde reductase,Aiar,AKR7,Akr7a2,Aldo keto reductase family 7,Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase,Aldo keto reductase family 7 member A2,Aldo keto reductase family 7,member A2 (aflatoxin aldehyde reductase),Aldoketoreductase 7,ARK72,SSA reductase,Succinic semialdehyde reductase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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