Anti-Human/Mouse/Rat AKAP10 Polyclonal Antibody

This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins bind to the regulatory subunits of protein kinase A (PKA) and confine the holoenzyme to discrete locations within the cell. The encoded protein is localized to mitochondria and interacts with both the type I and type II regulatory subunits of PKA. Polymorphisms in this gene may be associated with increased risk of arrhythmias and sudden cardiac death.AKAP10 (A-Kinase Anchoring Protein 10) is a Protein Coding gene. Diseases associated with AKAP10 include Cardiac Conduction Defect and Sudden Cardiac Death. Among its related pathways are Activation of cAMP-Dependent PKA and Factors involved in megakaryocyte development and platelet production.