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Anti-Human/Mouse/Rat ADAM17 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08118
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human ADAM17
Specificity Ubiquitously expressed. Expressed at highest levels in adult heart, placenta, skeletal muscle, pancreas, spleen, thymus, prostate, testes, ovary and small intestine, and in fetal brain, lung, liver and kidney.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P78536
Concentration 0.2 mg/mL
Dilution IHC 1:15-1:50
Formulation
Application IHC,ELISA
Other Names A disintegrin and metalloproteinase domain 17 (tumor necrosis factor,alpha,converting enzyme),A disintegrin and metalloproteinase domain 17,ADA17,ADAM 17,ADAM metallopeptidase domain 17,ADAM17,ADAM17 protein,CD 156b,CD156b,CD156b antigen,CSVP,Disintegrin and metalloproteinase domain-containing protein 17,MGC71942,NISBD,NISBD1,Snake venom like protease,Snake venom-like protease,TACE,TNF alpha convertase,TNF alpha converting enzyme,TNF-alpha convertase,TNF-alpha-converting enzyme,Tumor Necrosis Factor Alpha Converting Enzyme
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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