Anti-Human/Mouse/Rat Acetyl-E2F4 (Lys96) Polyclonal Antibody

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F-4 binds with high affinity to RBL1 and RBL2. In some instances, can also bind RB protein.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01420
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the human E2F-4 around the acetylation site of K96.
Specificity Found in all tissue examined including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q16254
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names E2F 4,E2F transcription factor 4,E2F transcription factor 4 p107/p130 binding,E2F-4,E2F4,E2F4,p107/p130 binding protein,Transcription factor E2F 4,Transcription factor E2F4
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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