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Anti-Human/Mouse/Rat 14-3-3 theta Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA08103
Size 100μl
Host Type Rabbit
Immunogen Synthetic peptide of human YWHAQ
Specificity Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P27348
Concentration 0.5 mg/mL
Dilution WB 1:1000-1:5000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names 14 3 3 protein T cell,14 3 3 protein tau,14 3 3 protein theta,14 3 3 tau,14 3 3 theta,14-3-3 protein T-cell,14-3-3 protein tau,14-3-3 protein theta,1433T,1C5,HS1,KCIP1,Protein HS1,Protein kinase C inhibitor protein 1,Protein tau,tyr3/trp5 monooxygenase activation protein,theta,Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein,theta polypeptide,Ywhaq
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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