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Anti-Human/Mouse RAD17 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA07687
Size 100μl
Host Type Rabbit
Immunogen Fusion protein of human RAD17
Specificity Overexpressed in various cancer cell lines and in colon carcinoma (at protein level). Isoform 2 and isoform 3 are the most abundant isoforms in non irradiated cells (at protein level). Ubiquitous at low levels. Highly expressed in testis, where it is expressed within the germinal epithelium of the seminiferous tubuli. Weakly expressed in seminomas (testicular tumors).
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O75943
Concentration 0.4 mg/mL
Dilution WB 1:200-1000, ELISA 1:1000-2000
Formulation
Application WB,ELISA
Other Names CCYC,Cell cycle checkpoint protein,Cell cycle checkpoint protein RAD17,FLJ41520,HRAD 17,hRad17,R24L,Rad 17,Rad 24,RAD1 (S. pombe) homolog,RAD1 homolog,RAD17,RAD17 homolog (S. pombe),RAD17 homolog,Rad17 like protein,RAD17,S. pombe,homolog of,RAD17,RAD17Sp,Rad24,Rad24,mouse,homolog of,Rad24,S. cerevisiae,homolog of,RF C activator 1 homolog,RF C/activator 1 homolog,RF-C/activator 1 homolog
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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