Anti-Human/Mouse PTRH2 Polyclonal Antibody

PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA10313
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human PTRH2
Specificity
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q9Y3E5
Concentration 0.1 mg/mL
Dilution WB 1:1000-1:5000, IHC 1:10-1:50
Formulation
Application WB,IHC,ELISA
Other Names Bcl 2 inhibitor of transcription 1,Bcl-2 inhibitor of transcription 1,BIT 1,BIT1,CGI 147,CGI147,mitochondrial,Peptidyl tRNA hydrolase 2 mitochondrial,Peptidyl-tRNA hydrolase 2,PTH 2,PTH2,PTH2,PTRH 2,PTRH2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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