Anti-Human/Mouse PSAP Polyclonal Antibody

This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11358
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human ACPP
Specificity Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Isoform 2 also expressed in the sarcolemma of skeletal muscle. Levels of this cellular isoform decreased in prostate cancer.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P15309
Concentration 0.3 mg/mL
Dilution WB 1:200-1:1000
Formulation
Application WB,ELISA
Other Names 5'-NT,5'-nucleotidase,Acid phosphatase prostate,ACP 3,ACP3,acpP,Ecto-5'-nucleotidase,PAP,PPAP,Prostatic acid phosphatase,Prostatic acid phosphotase,Thiamine monophosphatase,TMPase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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