Anti-Human/Mouse PRAF2 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

JM4 (Jena-Muenchen 4), also known as PRAF2 (PRA1 domain family, member 2), is a 178 amino acid endosomal multi-pass membrane protein involved in vesicular trafficking and Endoplasmic reticulum/Golgi transport. As a member of the PRA1 family, JM4 contains four putative transmembrane (TM) domains, interacts with the CC chemokine receptor 5 (CCR5) and colocalizes with Calnexin in the ER and mannose 6-phosphate receptor (CD-MPR) in the Golgi apparatus.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA10890
Size	100μl
Host Type	Rabbit
Immunogen	Synthetic peptide of human PRAF2
Specificity	Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non-neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	O60831
Concentration	0.4 mg/mL
Dilution	WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application	WB,IHC,ELISA
Other Names	Jena Muenchen 4,JM 4,PRA1 domain family member 2,PRA1 family protein 2,PRAF2,PRAF2
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse PRAF2 Polyclonal Antibody

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