Anti-Human/Mouse PPP1R13B Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]

The protein plays a central role in regulation of apoptosis via its interaction with p53/TP53.Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.It contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins.

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Properties

Data Sheet	Click for Datasheet
Catalog Number	PA10839
Size	100μl
Host Type	Rabbit
Immunogen	Synthetic peptide of human ASPP1
Specificity	Reduced expression in breast carcinomas expressing a wild-type TP53 protein.
Isotype	IgG
Reacitivity	Human,Mouse
Clone
Uniprot	Q96KQ4
Concentration	0.4 mg/mL
Dilution	IHC 1:25-1:100
Formulation
Application	IHC,ELISA
Other Names	Apoptosis-stimulating of p53 protein 1,ASPP1,p53BP2 like,p85,Ppp1r13b,Protein phosphatase 1 regulatory subunit 13B
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human/Mouse PPP1R13B Polyclonal Antibody

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