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Anti-Human/Mouse PIAS1 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. In vitro, binds A/T-rich DNA. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context. Together with PRMT1, may repress STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA05579
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the N-terminal region of human PIAS 1
Specificity Expressed in numerous tissues with highest level in testis.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O75925
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names AR interacting protein,DDXBP1,DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1,DEAD/H box binding protein 1,DEAD/H box-binding protein 1,E3 SUMO-protein ligase PIAS1,GBP,Gu binding protein,Gu-binding protein,GU/RH-II,Pias1,PIAS1,Protein inhibitor of activated STAT protein 1,Protein inhibitor of activated STAT,1,RNA helicase II binding protein,RNA helicase II-binding protein,Zinc finger,MIZ-type containing 3,ZMIZ3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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