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Anti-Human/Mouse Phospho-PER2 (Ser662) Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic Nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01823
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Per2 around the phosphorylation site of Ser662
Specificity Widely expressed. Found in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. High levels in skeletal muscle and pancreas. Low level in lung.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O15055
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
Formulation
Application WB,IHC-p,ELISA
Other Names Circadian clock protein PERIOD 2,FASPS,FASPS1,hPER 2,hPER2,KIAA0347,OTTHUMP00000164476,PER 2,PER2,PER2,Period 2,Period 2 isoform 1,Period circadian clock 2,Period circadian protein 2,Period circadian protein homolog 2,Period homolog 2 (Drosophila),Period homolog 2,Period,Drosophila,homolog of,2,Period2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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